What ingredients are in Cbi Twin Pso?2021-06-28T09:08:05+00:00

• Formulation in drops: Tocopheryl acetate 15%, cannabidiol, cyclopentasiloxane, orzya sativa song il, argania spinosa kernel oil.

• Cream formulation: Cbd, Allantoin, Panthenol, aqua, oleaeuropaeafruitoil, cetylpalmitate, prunus amygdalus dulcis oil, ethylhexyl palmitate, isopropyl myristate, cera alba, cetearyl alcohol, borago officinalis seed oil, cetearyl glucoside, phenoxycerylfed lauroylarginate hcl, tocopheryl acetate, sodium hydroxide.

What is CBi Skin Relief and what is it for?2021-06-28T09:07:32+00:00

Cbi Skin Relief is a moisturizing and soothing cream. Which contains CBD with an anti-inflammatory effect and allantoin with a keratolytic and re-epithelizing action, like urea.
Various studies suggest that it acts by promoting the proliferation of fibroblasts and the consequent synthesis of the extracellular matrix.

How is Cbi Skin Relief used?2021-06-28T09:07:16+00:00

Apply the product on the reddened and / or irritated area, massaging gently until completely absorbed. It is recommended to repeat the application twice a day.

What ingredients are in Cbi Skin Relief?2021-06-28T09:06:54+00:00

Aqua, Glycerin, Hydrogenated ethylexyl olivate, Oryza sativa bran oil, Prunus amygdalus dulcis oil, Cetearyl alcohol, Cetyl palmitate, Cannabidiol, C12-15 alkyl benzoate, Diglycerin, Phenoxyethanol, Hydrogenated olive oil unsaponifiables, Sodium benzoate, Aloe barbadensis leaf juice, Cera alba, Tocopheryl acetate, Cetearyl glucoside, Triisostearin, Butyrospermum parkii butter, Xanthan gum, Ceteareth-25, Ceteth-2, Potassium sorbate, Sodium lactate, Sodium PCA, Dimethicone, Glyceryl stearate, Allantoin, Hydroxyethylcellulose, Lauryl alcohol, Myristyl alcohol, Pinus pinaster bark/bud extract, Caprylyl glycol, Glyceryl caprylate, Citric acid, Fructose, Glycine, Inositol, Lactic acid, Niacinamide, Urea, Colloidal silver.


What is CBi GEL ITCH and what is it for?2021-06-28T09:04:45+00:00

Cbi Gel Itch is a product for the treatment of dermatological itching. The high concentration of CBD (3%) has an anti-inflammatory and antioxidant action, it targets immune cells, keratinocytes and sebocytes through cannabinoid receptors with consequent suppression of immune and inflammatory processes.

How is CBi GEL ITCH used?2021-06-28T09:04:22+00:00

Apply the product to the itchy area, massaging gently. Also indicated for mucous membranes and external genitals.
It is recommended to repeat the application twice a day.

What ingredients are in CBi GEL ITCH?2021-06-28T09:04:05+00:00

Prunus amygdalus dulcis oil, Caprylic / capric triglyceride, Cannabidiol, Silica dimethyl silylate, Myrcene, Cymbopogon flexuosus herb oil, Cananga odorata flower oil.

Is the CBI line natural?2021-06-28T09:03:20+00:00

The ingredients of the CBi line are of natural origin, free of hormones and estrogens.

What is CBD?2021-06-28T09:02:25+00:00

Cannabidiol (CBD) is a natural compound derived from the cannabis plant rich in pain-relieving, relaxing, anxiolytic properties and capable of providing excellent therapeutic benefits for topical use. It is a molecule of great interest because it is very effective and has no psychotropic effects.

Why is CBD used dermatologically?2021-06-28T09:02:05+00:00

The cutaneous Endocannabinoid System (SEC) has been demonstrated in the skin not only at the level of neuronal endocannabinoids: the endocannabinoids anandamide and 2-arachidonoylglycerol (2-AG), the CB1, CB2 and TRPV1 receptors and the enzymes involved in the biosynthesis and degradation of endocannabinoids (FAAH, MAGL, etc …).
The components of the SEC have been found, to varying degrees, on almost all the cells that make up the skin: epidermal keratinocytes, melanocytes, mast cells, fibroblasts, sebocytes, sweat glands and even on some types of hair follicles. In the skin, the role of the SEC is that of regulator of various functions: cell growth, proliferation and apoptosis, inflammatory and immune responses, transmission of sensory stimuli to the central nervous system and synthesis of lipids and other components of the epidermis.

As for Psoriasis, the treatments currently available range from the use of topical preparations – containing emollients, vitamin D analogues, cortisone, etc … – and phototherapy for mild-moderate forms, up to the use of systemic therapies with cyclosporine. , methotrexate, and biologics, for the more severe forms.

Despite the effectiveness of these treatments, the significant side effects they entail, push for the search for new therapies.
Cannabinoids have shown promise in the treatment of psoriasis. Several mechanisms are proposed: antiproliferative effects on keratinocytes, inhibition of the action of immune cells (macrophages and lymphocytes), the release of inflammatory cytokines and angiogenesis. (2)
The CB2 receptors, due to their localization on immune cells, would seem to be those most involved in these actions. CB1 and PPARγ receptors also play an important role in psoriasis. Various pre-clinical studies have demonstrated the validity of phytocannabinoids or analogues which, by acting on these receptors, improve the symptoms of psoriasis.

Even in dermatitis, various researches show that modulating the action of the SEC could give good results. In a study conducted on laboratory animals, it was found that CB2 receptors are involved in contact dermatitis, so called because they are caused by contact with irritants or allergens: using both agonists and antagonists of CB2, there was an increase in inflammation , but, by using inverse agonists (which bind and inactivate the receptor), both systemically and topically, a decrease in inflammation was obtained.

Finally, in dermatological pruritus, the application of cannabinoids is very promising because both CB1 and CB2 receptors and TRPV1 are involved in this sensation

Can the CBi line cause me allergy or irritation?2021-06-28T09:01:23+00:00

Tests carried out on CBi confirmed the best possible results in terms of irritability and allergic risk.
It does not contain silicones, preservatives, parabens, synthetic chemicals and essential oils.

Who can I contact for any other questions or concerns?2021-06-28T09:01:04+00:00

For any questions or information you can write to us at: info@agorapharma.eu

Do i have to pay shipping costs?2021-06-28T09:00:28+00:00

Absolutely not, shipping is included in the price!

What are the payment methods you accept?2021-06-28T09:00:06+00:00

On our site you can pay by credit card, Amazon Pay and Cash on delivery. (to be defined)

How many days will I receive CBi products?2021-06-28T08:59:18+00:00

We guarantee delivery within 2 working days for orders placed from Monday to Friday before 1pm on the same day, while for orders placed after 1pm delivery will take place within 3 working days.
For islands and regions such as Basilicata, Calabria, Campania and Puglia the delivery may take a few more days.

Is it possible to order the product abroad?2021-06-28T08:58:47+00:00

Absolutely yes, we ship all over the world!

Is it possible to track my product?2021-06-28T08:58:07+00:00

Of course, as soon as you have made your purchase, you will receive an order confirmation email where you will find a link to be able to track your order at any time.

I have received a defective / damaged product, can I return it?2021-06-28T08:57:46+00:00

If you have encountered any problems with the order you placed, write to info@agorapharma.eu and our customer service will find a solution together with you.

Is it possible to cancel the order?2021-06-28T08:56:53+00:00

Once the payment has been made, it will not be possible to cancel the order.

How is Cbi Twin Pso used?2021-06-28T08:55:50+00:00

• Formulation in drops: from 5 to 15 drops depending on the size of the area to be treated, massaging gently until completely absorbed

• Cream formulation: after complete absorption of the drop formulation, apply the cream to the area to be treated Apply twice / day. Treatment to be repeated for 15 consecutive days.